The series follows The Gang, a group of five alcoholic, depraved underachievers who run Paddy's Pub, a run-down bar in South Philadelphia. They are dishonest, selfish, egotistical, ignorant, greedy, rude, unethical, arrogant, and antagonistic, and are often embroiled in controversial issues. Episodes usually find them hatching elaborate schemes, conspiring against one another or others for personal gain or the pleasure of watching their downfall.

Source: Wikipedia.org